Academic staff
Flavien CHARPENTIER
DR2 Inserm "Cardiac arrhythmias" team leader, l'institut du thorax, Inserm UMR_S1087, CNRS UMR_C9691Contact details
Inserm UMR1087, CNRS UMR6291 l'institut du thorax IRS-UN 8 quai Moncousu BP 70721 44007 Nantes cedex
- Office
- 234b
- Phone
- 0228080164 (n° interne : 320164)
- Flavien.Charpentier@univ-nantes.fr
Taught academic discipline(s)
Cardiac physiology
Research topics
Characterization of the pathophysiological mechanisms of cardiac arrhythmias and conduction defects from gene to integrated function).
Activities / Resume
Main ongoing research projects
1. Study of a mouse model of progressive cardiac conduction defects (Lenègre disease) related to Scn5a, the gene coding for the sodium channel Nav1.5.
2. Study of a mouse model of long QT syndrome linked to Scn5a.
3. Functional characterization of a novel gene for Brugada Syndrome, RRAD.
Technical Approaches:
ECG, endocavitary exploration, microelectrodes, patch-clamp, quantitative RT-PCR, western blot, immunolabeling, histology, gene transfer
Publications:
-Pub Med
1. Study of a mouse model of progressive cardiac conduction defects (Lenègre disease) related to Scn5a, the gene coding for the sodium channel Nav1.5.
2. Study of a mouse model of long QT syndrome linked to Scn5a.
3. Functional characterization of a novel gene for Brugada Syndrome, RRAD.
Technical Approaches:
ECG, endocavitary exploration, microelectrodes, patch-clamp, quantitative RT-PCR, western blot, immunolabeling, histology, gene transfer
Publications:
-Pub Med
Additional information
Flavien Charpentier is also the scientific director of Therassay core facility (http://www.therassay.com/?lang=en)
Mis à jour le 27 October 2024.